1-Iodo-4-nitrobenzene → HCID 21975327, 화합물

반응식

I[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[N:11]1([CH2:17][CH2:18][CH2:19][NH2:20])[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1>>[N:11]1([CH2:17][CH2:18][CH2:19][NH:20][C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1

참가 물질

반응물 2

HCID 124951-Iodo-4-nitrobenzene

HCID 61055N-(3-Aminopropyl)morpholine

생성물 1

HCID 21975327HCID 21975327, 화합물

실험 절차

Using 1-iodo-4-nitro-benzene (500 mg) instead of 1-bromo-3-nitro-benzene, and 3-morpholin-4-yl-propylamine (353 mg) instead of morpholine, in the same manner as Step A in Example 1-D-105, the desired compound was obtained (219 mg, 41%).

출처 및 근거

ORD 기록: ord-4b400211593047fa91bd529f1f6366a6
출처 데이터셋: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08022205B2

반응 노트

불러오는 중…