Chlorosulfamic acid → [2-[Tert-butyl(dimethyl)silyl]oxy-4-[4-(cyclopropylmethylamino)pyrrolo[2,3-d]pyrimidin-7-yl]cyclopentyl]methyl sulfamate

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH:8]([CH2:26][OH:27])[CH2:9][CH:10]([n:12]2[cH:13][cH:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[NH:21][CH2:22][CH:23]2[CH2:24][CH2:25]2)[CH2:11]1)([CH3:28])[CH3:29].[Cl:30][S:31](=[O:32])(=[O:33])[NH2:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH:8]([CH2:26][O:27][S:31](=[O:32])(=[O:33])[NH2:34])[CH2:9][CH:10]([n:12]2[cH:13][cH:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[NH:21][CH2:22][CH:23]2[CH2:24][CH2:25]2)[CH2:11]1)([CH3:28])[CH3:29]

참가 물질

반응물 2

HCID 24499Chlorosulfamic acid

HCID 70818817[2-[Tert-butyl(dimethyl)silyl]oxy-4-[4-(cyclopropylmethylamino)pyrrolo[2,3-d]pyrimidin-7-yl]cyclopentyl]methanol

생성물 1

HCID 88996177[2-[Tert-butyl(dimethyl)silyl]oxy-4-[4-(cyclopropylmethylamino)pyrrolo[2,3-d]pyrimidin-7-yl]cyclopentyl]methyl sulfamate

출처 및 근거

ORD 기록: ord-47130581cfd64fe196392470f7f5a709
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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