참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Stavudine DMPU | HCID 86625622 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Stavudine | HCID 18283 | 66.82% |
반응 단계
Stavudine DMPU solvate (20 g, 0.057 mole) is dissolved in water (20 ml) at 55° C. and the solution is allowed cooling on its own for an hour to crystallize. The mixture is further cooled on 0-5° C. for 2 hrs. The precipitated product is filtered, washed with acetone and dried to give 8.5 g (66.82%) of pure white crystalline Stavudine. HPLC results are given in Table-2
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08026356B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_09 |
|---|
| ORD ID | ord-c22b27eb05fb4b52934752f5d42be106 |
|---|
| 출처 메모 | uspto-grants-2011_09 |
|---|
