4-Methyl-1,2,3-thiadiazole-5-carbohydrazide → 1-{[5-(4-Methyl-1,2,3-thiadiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile
반응식
[C:1]([C:3]1[C:4]([C:16]([F:19])([F:18])[F:17])=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:12][C:13]([OH:15])=O)[CH:7]=[CH:6]2)#[N:2].[CH3:20][C:21]1[N:22]=[N:23][S:24][C:25]=1[C:26]([NH:28][NH2:29])=O>>[CH3:20][C:21]1[N:22]=[N:23][S:24][C:25]=1[C:26]1[O:15][C:13]([CH2:12][N:8]2[C:9]3[C:5](=[C:4]([C:16]([F:19])([F:18])[F:17])[C:3]([C:1]#[N:2])=[CH:11][CH:10]=3)[CH:6]=[CH:7]2)=[N:29][N:28]=1참가 물질
3
실험 절차
Synthesized as described in Example 35C from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and 4-methyl-1,2,3-thiadiazole-5-carbohydrazide: MS (ES) m/z 391 (M+1).
후처리
- customSynthesized
출처 및 근거
- ORD 기록