Trifluoroacetic acid → 5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole

HRID 913578노트

반응식

HRID 913578 반응식
[Br:1][C:2]1[C:3]([Cl:10])=[C:4]([NH2:9])[C:5]([NH2:8])=[CH:6][CH:7]=1.[C:11](O)([C:13]([F:16])([F:15])[F:14])=O>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]2[NH:8][C:11]([C:13]([F:16])([F:15])[F:14])=[N:9][C:4]=2[C:3]=1[Cl:10]

참가 물질

3

반응물 2

HCID 6422Trifluoroacetic acidHCID 578001544-Bromo-3-chlorobenzene-1,2-diamine

생성물 1

HCID 578003545-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole

실험 절차

Synthesized as described in Example 195C from 4-bromo-3-chloro-1,2-benzenediamine and TFA: MS (ESI) m/z 301 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-1a97aaa120dc409ebe56b09d5a0e9cb5
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08026262B2

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