5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole → 4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile

HRID 913579

반응식

HRID 913579 반응식
Br[C:2]1[CH:14]=[CH:13][C:5]2[NH:6][C:7]([C:9]([F:12])([F:11])[F:10])=[N:8][C:4]=2[C:3]=1[Cl:15].[C:16]([Cu])#[N:17]>>[Cl:15][C:3]1[C:4]2[N:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[NH:6][C:5]=2[CH:13]=[CH:14][C:2]=1[C:16]#[N:17]

참가 물질

3

반응물 2

HCID 578003545-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazoleHCID 178418546HCID 178418546, 화합물

생성물 1

HCID 674045324-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile

실험 절차

Synthesized as described in Example 197A from 5-bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole and CuCN: MS (APCl) m/z 246 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-673dbfcf8d964de6bb902be8f1ad9de6
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08026262B2

연결된 노트

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