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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 913700생성일: 2026년 10월 26일

2-Bromo-4-(chloromethyl)thiazole → 1-[(2-Bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913700

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-4-(chloromethyl)thiazoleHCID 16427149—
반응물2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 53309346—
생성물1-[(2-Bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404358—

반응 단계

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 2-bromo-4-(chloromethyl)-1,3-thiazole (Example 311A): MS (ES) m/z 400 (M+1) and 402 (M+1, isotope).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08026262B2
출처 데이터셋uspto-grants-2011_09
ORD IDord-11994fc471244e8db0de17e6b877e935
출처 메모uspto-grants-2011_09