2-Bromo-5-(chloromethyl)thiophene → HCID 67404974, 화합물

HRID 913704노트

반응식

HRID 913704 반응식
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:14])([F:13])[F:12])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2.[Br:17][C:18]1[S:19][C:20]([CH2:23]Cl)=[CH:21][CH:22]=1>>[Br:17][C:18]1[S:19][C:20]([CH2:23][N:3]2[C:4]3[C:9](=[C:8]([C:11]([F:12])([F:14])[F:13])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=3)[CH:10]=[C:2]2[CH3:1])=[CH:21][CH:22]=1

참가 물질

3

반응물 2

HCID 101982272-Bromo-5-(chloromethyl)thiopheneHCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

생성물 1

HCID 67404974HCID 67404974, 화합물

실험 절차

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 2-bromo-5-(chloromethyl)thiophene: MS (ES) m/z 399 (M+1) and 401 (M+1, isotope).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-33dd1238506c4059beb2975ac2c02487
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08026262B2

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