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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 913711생성일: 2026년 10월 26일

4-(Trifluoromethyl)phenylboronic acid → 2-Methyl-4-(trifluoromethyl)-1-{[4'-(trifluoromethyl)-3-biphenylyl]methyl}-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913711

반응식

참여 물질

역할이름HCID투입량
반응물4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
반응물1-[(3-Bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405035—
생성물2-Methyl-4-(trifluoromethyl)-1-{[4'-(trifluoromethyl)-3-biphenylyl]methyl}-1H-indole-5-carbonitrileHCID 86620703—

반응 단계

Synthesized as described in Example 310D using 1-[(3-bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 318A) and [4-(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 459 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08026262B2
출처 데이터셋uspto-grants-2011_09
ORD IDord-1690a66d9ae345a2805209cbcba7bea5
출처 메모uspto-grants-2011_09