Ethane, 1-(2-chloroethoxy)-2-methoxy- → 2-Methyl-1-(2-{[2-(methyloxy)ethyl]oxy}ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 913739

반응식

HRID 913739 반응식
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:14])([F:13])[F:12])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2.Cl[CH2:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH3:24]>>[CH3:1][C:2]1[N:3]([CH2:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH3:24])[C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:12])([F:14])[F:13])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2

참가 물질

3

반응물 2

HCID 94934Ethane, 1-(2-chloroethoxy)-2-methoxy-HCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

생성물 1

HCID 674066352-Methyl-1-(2-{[2-(methyloxy)ethyl]oxy}ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

실험 절차

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 1-chloro-2-{[2-(methyloxy)ethyl]oxy}ethane: MS (ES) m/z 327 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-08fdc3ec3dca451c8b0de58fe2c9ff3e
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08026262B2

연결된 노트

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