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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 913755생성일: 2026년 10월 26일

4-(Chloromethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole → 2-Cyclopropyl-4-(trifluoromethyl)-1-({2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913755

반응식

참여 물질

역할이름HCID투입량
반응물4-(Chloromethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazoleHCID 2736625—
반응물2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404472—
생성물2-Cyclopropyl-4-(trifluoromethyl)-1-({2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-1H-indole-5-carbonitrileHCID 86620717—

반응 단계

Synthesized as described in Example 4 using 2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 165A) and 4-(chloromethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole: MS (ES) m/z 492 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08026262B2
출처 데이터셋uspto-grants-2011_09
ORD IDord-39972938611f49f6b2235d0882dddb01
출처 메모uspto-grants-2011_09