Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → (6-(3-(3-Methylphenyl)aminocarbonylamino-propanoyl)-2-benzothiazolyl)-3-ethylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Isocyanate | HCID 105034 | — |
| 반응물 | 1-(6-(3-Aminopropanoyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985556 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (6-(3-(3-Methylphenyl)aminocarbonylamino-propanoyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985584 | 25% |
반응 단계
Similar to the synthesis of Example 249, a mixture of 1-(6-(3-aminopropanoyl)-2-benzothiazolyl)-3-ethylurea, triethylamine and 3-methylphenhyl isocyanate in DMF was reacted to give the desired compound 0.021 g (25%). LC/MS 426.1 (M+1); LC retention time 2.94 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091227B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-3b86cf3eeca34ce7947e49ad0db3feaf |
| 출처 메모 | uspto-grants-2006_08 |