Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Cephalexin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Amino-2-phenylacetamide | HCID 12791 | — |
| 반응물 | 7-Aminodeacetoxycephalosporanic acid | HCID 33498 | — |
| 반응물 | Penicillin G Potassium | HCID 23664709 | — |
| 생성물 | Cephalexin | HCID 27447 | — |
반응 단계
The reaction is carried out at 25° C. and pH 7.5 in a fixed bed reactor. 10 ml of an aqueous solution of a mixture 0.2 M 7-ADCA and 0.2 M D-phenylglycinamide are passed through a column with 0.5 ml of the immobilized penicillin amidase. During the reaction, the pH is kept constant by adding HCl in an attached stirred reservoir container. Samples are taken and analyzed by HPLC as shown in example 5 at particular time intervals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07264943B2 |
| 출처 데이터셋 | uspto-grants-2007_09 |
| ORD ID | ord-76ae13ba93db4ce78e8e70f1e9a58fcd |
| 출처 메모 | uspto-grants-2007_09 |