Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 1-(6-(3-(3-Tolyl)aminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | m-Tolyl isocyanate | HCID 69303 | — |
| 반응물 | 1-(6-(3-Aminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985575 | — |
| 반응물 | 1-(6-(3-Phenylaminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985625 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-(6-(3-(3-Tolyl)aminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985513 | 26% |
반응 단계
Similar to the synthesis of 1-(6-(3-phenylaminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea, a mixture of 1-(6-(3-aminophenyl)-2-benzothiazolyl)-3-ethylurea, triethylamine, and 3-tolyl isocyanate in toluene was reacted to give the desired compound 0.023 g (26%). LC/MS 446.2 (M+1); LC retention time 3.76 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091227B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-539abe6e916e46699d709602a0ec92f3 |
| 출처 메모 | uspto-grants-2006_08 |