Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 9152생성일: 2026년 10월 23일
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → N-Ethyl-N'-[7-(3-pyridyl)[1,3]thiazolo[4',5': 3,4]benzo[d][1,3]thiazol-2-yl]urea
https://huagongshe.com/ko/reaction/9152
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone | HCID 6775 | — |
| 반응물 | N-Ethyl-N'-[7-(3-pyridyl)-4,5-dihydro[1,3]thiazolo[4',5': 3,4]benzo[d][1,3]thiazol-2-yl]urea | HCID 86588975 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-Ethyl-N'-[7-(3-pyridyl)[1,3]thiazolo[4',5': 3,4]benzo[d][1,3]thiazol-2-yl]urea | HCID 9924797 | 30.1% |
반응 단계
A suspension of N-ethyl-N′-[7-(3-pyridyl)-4,5-dihydro[1,3]thiazolo[4′,5′: 3,4]benzo[d]-[1,3]thiazol-2-yl]urea (10 mg, 0.028 mmol) and DDQ (13 mg, 0.056 mmol) in toluene (1 mL) was heated to about 35° C. for about 3 hrs. The reaction mixture was concentrated in vacuo and purified by preparative HPLC. 3 mg (30%) pure product was isolated. LC/MS 356 (MH+); RP-HPLC 14.25 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07091227B2 |
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| 출처 데이터셋 | uspto-grants-2006_08 |
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| ORD ID | ord-990155086c5549828f0ac2fa7edc056a |
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| 출처 메모 | uspto-grants-2006_08 |
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