N-p-Bromophenylthiourea → N-[7-(4-Bromoanilino)-4,5-dihydro[1,3]thiazolo[4',5': 3,4]benzo[d][1,3]thiazol-2-yl]-N'-ethylurea

참여 물질

역할	이름	HCID	투입량
반응물	N-p-Bromophenylthiourea	HCID 2735620	—
반응물	1-(6-Bromo-7-oxo-4,5,6,7-tetrahydro-2-benzothiazolyl)-3-ethyl-urea	HCID 21985543	—
용매	Tetrahydrofuran	HCID 8028	—
생성물	N-[7-(4-Bromoanilino)-4,5-dihydro[1,3]thiazolo[4',5': 3,4]benzo[d][1,3]thiazol-2-yl]-N'-ethylurea	HCID 86588976	—

반응 조건

온도	65 °C

반응 단계

A suspension of N-(6-bromo-7-oxo-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-N′-ethylurea (50 mg, 0.16 mmol) and 4-bromo-phenyl-thiourea (36 mg, 0.16 mmol) in THF (1.0 mL) was heated to about 65° C. for about 1.5 hrs. The reaction mixture was pumped down and used in the next step without further purification.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07091227B2
출처 데이터셋	uspto-grants-2006_08
ORD ID	ord-ea8233a5c256454ba3ea6ba2c519a36d
출처 메모	uspto-grants-2006_08