참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Propynoic acid, 3-phenyl-, ethyl ester | HCID 91516 | — |
| 반응물 | 4-Phenyl-1,3-oxazole | HCID 589279 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Ethyl-4-phenyl-3-furoate | HCID 15037153 | 78.4% |
반응 단계
Mix 4-Phenyl oxazole (3.33 g, 23.0 mmol) and ethyl phenylpropiolate (4.0 g, 23.0 mmol) in a sealed tube and heat at 220° C. for 20 hours. Perform flash-chromatography on silica gel eluting with 4:1 Hex/ethyl acetate to afford 3.9 g of 4-phenylfuran-3-carboxylic acid ethyl ester as a yellow oil. MS: m/e=217 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07265246B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_09 |
|---|
| ORD ID | ord-9fd118029536481387b3a1242356d996 |
|---|
| 출처 메모 | uspto-grants-2007_09 |
|---|
