3-Chloro-2-fluoro-5-(trifluoromethyl)benzyl bromide → 7-[3-(3-Chloro-2-fluoro-5-trifluoromethylbenzyl)-4,4,4-trifluoro-3-hydroxy-1,1-dimethylbutyl]-2,3-dihydrobenzofuran-5-carbonitrile
반응식
[F:1][C:2]([F:21])([F:20])[C:3](=[O:19])[CH2:4][C:5]([C:8]1[C:16]2[O:15][CH2:14][CH2:13][C:12]=2[CH:11]=[C:10]([C:17]#[N:18])[CH:9]=1)([CH3:7])[CH3:6].[Cl:22][C:23]1[C:24]([F:35])=[C:25]([CH:28]=[C:29]([C:31]([F:34])([F:33])[F:32])[CH:30]=1)[CH2:26]Br>>[Cl:22][C:23]1[C:24]([F:35])=[C:25]([CH:28]=[C:29]([C:31]([F:33])([F:34])[F:32])[CH:30]=1)[CH2:26][C:3]([OH:19])([C:2]([F:1])([F:20])[F:21])[CH2:4][C:5]([C:8]1[C:16]2[O:15][CH2:14][CH2:13][C:12]=2[CH:11]=[C:10]([C:17]#[N:18])[CH:9]=1)([CH3:7])[CH3:6]참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared from 7-(4,4,4-trifluoro-1,1-dimethyl-3-oxobutyl)-2,3-dihydrobenzofuran-5-carbonitrile and 3-chloro-2-fluoro-5-trifluoromethylbenzyl bromide using the procedure described in Example 5.
출처 및 근거
- ORD 기록
- ord-21c12edf0a92453da9f9033c1aa594b8