1,3,5-Trimethyl-3,7-diazabicyclo(3.3.1)nonan-9-ol → HCID 69226257, 화합물

HRID 916342노트

반응식

HRID 916342 반응식
[C:1]([C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](F)=[CH:5][CH:4]=1)#[N:2].[OH:14][CH:15]1[C:20]2([CH3:25])[CH2:21][N:22]([CH3:24])[CH2:23][C:16]1([CH3:26])[CH2:17][NH:18][CH2:19]2>>[OH:14][CH:15]1[C:16]2([CH3:26])[CH2:23][N:22]([CH3:24])[CH2:21][C:20]1([CH3:25])[CH2:19][N:18]([C:6]1[C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:3]([C:1]#[N:2])=[CH:4][CH:5]=1)[CH2:17]2

참가 물질

3

반응물 2

HCID 5415011,3,5-Trimethyl-3,7-diazabicyclo(3.3.1)nonan-9-olHCID 27367341-Cyano-4-fluoronaphthalene

생성물 1

HCID 69226257HCID 69226257, 화합물수율 8%

실험 절차

The title compound (3 mg, 8% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 9-hydroxy-1,5,7-trimethyl-3,7-diazabicyclo[3.3.1]nonane (86 mg, 0.468 mmol).

출처 및 근거

ORD 기록
ord-6573876a409c449daf82c3284856dce9
출처 데이터셋
uspto-grants-2007_09
특허 번호
US07268232B2

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