Probucol → HCID 178460887, 화합물

HRID 916988

반응식

CC(C1C=C(S[C:17]([S:20][C:21]2[CH:26]=[C:25]([C:27]([CH3:30])([CH3:29])[CH3:28])[C:24]([OH:31])=[C:23]([C:32]([CH3:35])([CH3:34])[CH3:33])[CH:22]=2)([CH3:19])[CH3:18])C=C(C(C)(C)C)C=1O)(C)C.C(OC1[O:43][C@@H:42]([CH2:44][OH:45])[C@@H:41]([CH2:46]O)[O:40]1)C>>[C:32]([C:23]1[CH:22]=[C:21]([SH:20]([CH:17]([CH3:18])[CH3:19])[S:20][C:21]2[CH:22]=[C:23]([C:32]([CH3:33])([CH3:34])[CH3:35])[C:24]([OH:31])=[C:25]([C:27]([CH3:30])([CH3:29])[CH3:28])[CH:26]=2)[CH:26]=[C:25]([C:27]([CH3:30])([CH3:28])[CH3:29])[C:24]=1[O:31][CH2:46][C@H:41]([OH:40])[C@H:42]([OH:43])[CH2:44][OH:45])([CH3:33])([CH3:35])[CH3:34]

참가 물질

반응물 2

HCID 4912Probucol

HCID 694944892-ethoxy-1,3-dioxolane-4(S),5(R)-dimethanol

생성물 1

HCID 178460887HCID 178460887, 화합물

실험 절차

The title compounds can be prepared using the same procedure as described in Ex-1 starting from probucol and 2-ethoxy-1,3-dioxolane-4(S),5(R)-dimethanol and performing a chiral separation.

후처리

customa chiral separation

출처 및 근거

ORD 기록: ord-887cedfb02244efb9e1162d00378d83d
출처 데이터셋: uspto-grants-2007_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07271274B2

연결된 노트

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