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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 917638생성일: 2026년 10월 26일

Thionyl Chloride → 4-(3-Chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidine

https://huagongshe.com/reaction/917638

반응식

참여 물질

역할이름HCID투입량
반응물Thionyl ChlorideHCID 24386—
반응물4-(3-Chloro-4-methoxybenzylamino)-5-carboxy-6-chloro-2-methylthiopyrimidineHCID 17848268—
생성물4-(3-Chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidineHCID 17848283—

반응 단계

A mixture of 4-(3-chloro-4-methoxybenzylamino)-5-carboxy-6-chloro-2-methylthiopyrimidine 500 mg and thionyl chloride 2 ml is refluxed for 10 minutes. After reaction thionyl chloride is removed and the solvent is removed in azeotrope with methylene chloride to give 4-(3-chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07273868B2
출처 데이터셋uspto-grants-2007_09
ORD IDord-dc5862c448ac4e0bab6c22929823c09d
출처 메모uspto-grants-2007_09