Hydrazine → 3,5-Diphenyl-1H-pyridazin-4-one

HRID 917813노트

반응식

HRID 917813 반응식
C([N:3](CC)[CH:4]=[C:5]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:6](=[O:15])[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=O)C.[NH2:24]N>C(O)(C)C>[C:9]1([C:7]2[C:6](=[O:15])[C:5]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:4][NH:3][N:24]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 539328324-(Diethylamino)-1,3-diphenylbut-3-ene-1,2-dione

생성물 1

HCID 6192033,5-Diphenyl-1H-pyridazin-4-one

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

The product solution from Example 1 was cooled to 0°C. and mixed with 20 ml. of isopropyl alcohol and 2 ml. of hydrazine. The mixture was stirred for 10 minutes, and was then warmed to room temperature and stirred for 15 hours. The product was then collected by filtration. The yield was 6.0 g. of 3,5-diphenyl-4(1H)-pyridazinone, m.p. 328°-32°C., which was identified by infrared and nuclear magnetic resonance analysis.

후처리

  1. additionmixed with 20 ml
  2. stirringstirred for 15 hours
  3. filtrationThe product was then collected by filtration

출처 및 근거

ORD 기록
ord-34e2931cac64401982439a3cc562be6e
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03967952

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