Ethanol → Ethyl (4-cyclohexylphenyl)acetate

HRID 917917노트

반응식

HRID 917917 반응식
[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH2:13][C:14]#N)=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:16]([OH:18])[CH3:17].S(=O)(=O)(O)[OH:20]>O>[CH2:16]([O:18][C:14](=[O:20])[CH2:13][C:10]1[CH:11]=[CH:12][C:7]([CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:8][CH:9]=1)[CH3:17]

참가 물질

5

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 2024547429030-58-8

생성물 1

HCID 53423226Ethyl (4-cyclohexylphenyl)acetate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

13.7 g of para-cyclohexyl-phenylacetonitrile, 21 ml of absolute ethanol, and 7.3 ml of concentrated sulfuric acid are boiled overnight. The mixture is then diluted with water and extracted several times with ethyl acetate. The solution is washed with sodium bicarbonate solution and water, and dried over sodium sulfate. The residue obtained on evaporation of the solvent is distilled in a high vacuum. There is obtained para-cyclohexylphenyl acetic acid ethyl ester boiling at 125°-127°C under a pressure of 0.5 mm of Hg.

후처리

  1. extractionextracted several times with ethyl acetate
  2. washThe solution is washed with sodium bicarbonate solution and water
  3. dry with materialdried over sodium sulfate
  4. customThe residue obtained on evaporation of the solvent
  5. distillationis distilled in a high vacuum

출처 및 근거

ORD 기록
ord-b01f2d2809f54fd983e92686012e8f8e
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03968142

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