Bromine → 2-[Bromo(nitro)methylidene]-1-methylimidazolidine

HRID 918040노트

반응식

HRID 918040 반응식
[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[CH:7][N+:8]([O-:10])=[O:9].[Br:11]Br>O>[Br:11][C:7]([N+:8]([O-:10])=[O:9])=[C:3]1[NH:4][CH2:5][CH2:6][N:2]1[CH3:1]

참가 물질

4

반응물 2

HCID 24408BromineHCID 702500461-Methyl-2-(nitromethylidene)imidazolidine2회

생성물 1

HCID 706389552-[Bromo(nitro)methylidene]-1-methylimidazolidine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A stirred solution of 3.57 grams of 1-methyl-2(nitromethylene)imidazolidine (Compound 1) in 25 milliliters of water was treated dropwise with 3.99 grams of bromine at room temperature. After 30 minutes, the reaction mixture was extracted with methylene chloride. The extract was dried (MgSO4) and the solvent was evaporated to give 3.0 grams of crude product, melting point 100° (with vigorous decomposition). Recrystallization of the crude product from methylene chloride gave 15, melting point: 97° (explodes).

후처리

  1. extractionthe reaction mixture was extracted with methylene chloride
  2. dry with materialThe extract was dried (MgSO4)
  3. customthe solvent was evaporated
  4. customto give 3.0 grams of crude product, melting point 100° (with vigorous decomposition)
  5. customRecrystallization of the crude product from methylene chloride

출처 및 근거

ORD 기록
ord-aba6bbb82a6a497eb5fecfac18c2958d
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03969354

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