Diethyl Ether → Dec-2-YN-1-YL 7-cyclopropylheptanoate

HRID 918118

반응식

HRID 918118 반응식
CCOCC.[CH:6]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15](Cl)=[O:16])[CH2:8][CH2:7]1.[CH2:18]([OH:28])[C:19]#[C:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>N1C=CC=CC=1>[CH:25]1([CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][C:18]([O:16][CH2:15][C:14]#[C:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:6][CH2:7][CH3:8])=[O:28])[CH2:27][CH2:26]1

참가 물질

5

반응물 3

HCID 3283Diethyl EtherHCID 777632-Decyn-1-olHCID 214896707-Cyclopropylheptanoyl chloride

생성물 1

HCID 21522904Dec-2-YN-1-YL 7-cyclopropylheptanoate

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To 60 ml. anhydrous ether and 1.5 g. 7-cyclopropylheptanoyl chloride is added 1.2 g. 2-decyn-1-ol. The mixture is cooled to 0° and 0.8 ml. pyridine is added. The solution is stirred at room temperature for 1 day. The product is worked up using the procedure of Example 1C to yield 2-decynyl 7-cyclopropylheptanoate.

후처리

  1. temperatureThe mixture is cooled to 0°

출처 및 근거

ORD 기록
ord-b6fd8f9e5d76496d92069b0db6a0a953
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03969384

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