참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (S)-Ethyl 3-amino-3-phenylpropanoate | HCID 915085 | — |
| 반응물 | Potassium alloy, nonbase, K,Na | HCID 16211683 | — |
| 생성물 | (R)-Ethyl 3-amino-3-phenylpropanoate | HCID 915086 | 93.1% |
반응 단계
In a 25 ml flask, 13.0 g of D-β-phenylalanine ethyl ester was charged under nitrogen, and sodium-potassium alloy (Na : K = 56 : 44 by weight) (0.1 g) was added thereto. The mixture was stirred at 20°C for 3 hours. The reaction mixture was treated as in Example 11 to give 12.1 g of racemic β-phenylalanine ethyl ester. B.P. 95° to 96°C/0.6 mmHg. [α]D25 -0.1° (neat).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US03970700 |
|---|
| 출처 데이터셋 | uspto-grants-1976_07 |
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| ORD ID | ord-d96040b264dc47d38633722070ebf611 |
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| 출처 메모 | uspto-grants-1976_07 |
|---|
