참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | N,N-Dimethyl-3-nitroaniline | HCID 69269 | — |
| 생성물 | 4-Dimethylamino-2-nitrobenzaldehyde | HCID 291352 | 66% |
반응 단계
720 parts of phosphorus oxychloride is added at 25°C to a solution of 498 parts of m-nitrodimethylaniline in 1800 parts by volume of dimethylformamide. The mixture is then heated within 1 hour to 75° to 80°C and stirred at this temperature for six hours. After the solution has cooled it is poured into 6000 parts of ice-water. The precipitate is suction filtered, washed and recrystallized from acetone. 385 parts (66% of theory) of 2-nitro-4-dimethylaminobenzaldehyde having a melting point of 115° to 116°C is obtained. ##SPC14##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US03971821 |
|---|
| 출처 데이터셋 | uspto-grants-1976_07 |
|---|
| ORD ID | ord-d34ef8ca76e045609c7476aab3f3ae63 |
|---|
| 출처 메모 | uspto-grants-1976_07 |
|---|
