Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 2-Bromo-p-chlorophenylacetyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2-Bromo-4-chlorophenylacetic acid | HCID 21828503 | — |
| 생성물 | 2-Bromo-p-chlorophenylacetyl chloride | HCID 19794234 | 88.2% |
반응 단계
28.3g (0.113 mol) of 2-bromo-p-chlorophenylacetic acid was mixed with 26.9g (0.226 mol) of thionylchloride and the mixture was refluxed for 2.5 hours. After the excess thionylchloride had been distilled off, the reaction mixture was distilled under reduced pressure to give 26.7g of 2-bromo-p-chlorophenylacetyl chloride as yellow-orange oil. (b.p. 148° - 152°C/15 mmHg)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03971828 |
| 출처 데이터셋 | uspto-grants-1976_07 |
| ORD ID | ord-0a9b9b78ae254be2987c42d7e132ee20 |
| 출처 메모 | uspto-grants-1976_07 |