Ammonia → 3-Nitro-4-phenoxy-5-sulphamyl-benzamide

HRID 918652노트

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HRID 918652 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7](Cl)=[O:8])([O-:3])=[O:2].[NH3:24]>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([NH2:24])=[O:8])([O-:3])=[O:2]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 215060353-Nitro-4-phenoxy-5-sulfamoylbenzoyl chloride

생성물 1

HCID 215060723-Nitro-4-phenoxy-5-sulphamyl-benzamide

실험 절차

3-Nitro-4-phenoxy-5-sulphamyl-benzoyl chloride (4 g) was added in portions to liquid ammonia (40 ml). Then excess of ammonia was distilled off, and the residue was triturated with water (50 ml). The precipitated 3-nitro-4-phenoxy-5-sulphamyl-benzamide was isolated by filtration and recrystallized twice from aqueous ethanol. After drying in vacuo, the compound was obtained with a melting point of 255°-256°C.

후처리

  1. distillationThen excess of ammonia was distilled off
  2. customthe residue was triturated with water (50 ml)

출처 및 근거

ORD 기록
ord-b5fd12e597c945a384442a5e7f92d1d4
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03971819

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