3-Bromoquinoline → HCID 178519901, 화합물

온도

100 °C

- reaction input `pd_catalyst` was added as a solution (2-methyltetrahydrofuran 1 mmol/L) and then the solvent was removed to leave solid solute before adding other reactants/reagents; - stirrer was added after `pd_catalyst` and before `base`; - reaction inputs were prepared inside a glove box but the reaction itself did not happen in a glove box; - the reaction vial was sealed after adding all reaction inputs

1. temperatureThe reactions were then allowed to cool to room temperature
2. additionEach reaction vial was diluted with 500 uL of a pre-prepared solution consisting of 1 umol dibenzylaniline (labelled as an internal standard for the purposes of PyParse analysis) and 20 umol dimethylsulfoxide in acetonitrile.
3. stirringThe reactions were sealed and shaken to ensure a homogenous mixture.
4. aliquot50 uL of each reaction mixture was then aspirated and dispensed to the analysis plate.
5. additionEach well of the analysis plate was diluted with 150 uL of dimethylsulfoxide, and the analysis plate was sealed with polypropylene film.

ORD 기록

ord-185a58720cdb4417ab5c4eb35dc52b68

출처 데이터셋

C-H activation of oxazoles from the second demo case in the PyParser paper

DOI

10.1039/d3dd00167a