2-Chloro-6-fluorobenzylamine → 6-Bromo-N-(2-chloro-6-fluorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918845

반응식

HRID 918845 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][NH2:10].[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21](OCC)=[O:22])[N:20]=2)[CH:17]=1>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21]([NH:10][CH2:9][C:3]3[C:4]([F:8])=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[O:22])[N:20]=2)[CH:17]=1

참가 물질

3

반응물 2

HCID 848332-Chloro-6-fluorobenzylamineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

생성물 1

HCID 1181139026-Bromo-N-(2-chloro-6-fluorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

실험 절차

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2-chloro-6-fluorophenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

출처 및 근거

ORD 기록
ord-dc5dd599e77e4860b04fe4495bdc94fd
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09271969B2

연결된 노트

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