Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Iodide → 3-Cyclopentyloxy-4-methoxybenzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 3-Hydroxy-4-methoxybenzyl alcohol | HCID 78089 | — |
| 반응물 | Cyclopentyloxy-bromide | HCID 21697665 | — |
| 생성물 | 3-Cyclopentyloxy-4-methoxybenzyl alcohol | HCID 11138706 | 35.8% |
반응 단계
From 3-hydroxy-4-methoxybenzyl alcohol (50 g, 0.324 mol), cyclopentyloxybromide (70 ml, 0.648 mol), caesium carbonate (72.83 g, 0.222 mol) and sodium iodide (5.63 g, 0.037 mol). Chromatography (SiO2 ; EtOAc-C6H14, 1:3) to yield the title compound (25.782 g). (Found C, 69.92; H, 8.18. C13H18O3 requires C, 70.25; H, 8.16).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723460 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-96b5709519a5432ab5539f7faa641c73 |
| 출처 메모 | uspto-grants-1998_03 |