3-Bromopyridine-4-carboxaldehyde → 1-(3-Bromo-pyridin-4-yl)-4-phenyl-butan-1-ol

반응식

[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=[O:9].[C:10]1([CH2:16][CH2:17][CH2:18][Mg]Br)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]([OH:9])[CH2:18][CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

참가 물질

반응물 2

HCID 27629973-Bromopyridine-4-carboxaldehyde

HCID 178418471HCID 178418471, 화합물

생성물 1

HCID 679637751-(3-Bromo-pyridin-4-yl)-4-phenyl-butan-1-ol

실험 절차

Prepared according to the procedure described in Example 5, Step 1, using the following starting materials: 3-bromo-pyridine-4-carbaldehyde and 3-phenyl-propyl magnesium bromide.

후처리

customPrepared

출처 및 근거

ORD 기록: ord-c4fad9c9d7064a0ca9cbf97a236323e3
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09272990B2

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