Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Nitrothiophene-2-carboxaldehyde → 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethoxy-1,3-benzothiazol-2yl)hydrazone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Nitrothiophene-2-carboxaldehyde | HCID 78281 | — |
| 반응물 | 5-Nitro-2-furaldehyde 2-(1,3-benzothiazole-2-yl)hydrazone | HCID 2856671 | — |
| 반응물 | 2-Hydrazinyl-6-(trifluoromethoxy)-1,3-benzothiazole | HCID 10422158 | — |
| 생성물 | 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethoxy-1,3-benzothiazol-2yl)hydrazone | HCID 86664233 | — |
반응 단계
The compound 3j was prepared according procedure described for 3a by employing 5-nitrothiophen aldehyde (157 mg, 1 mmol) and 2-hydrazino-6-trifluoromethoxy-benzothiazole (249 mg, 1 mmol) at 70° C. for 2 h (yield 219 mg, 75%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09273039B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-f77a14a2eeaf45e7b6abb5c9beed0994 |
| 출처 메모 | uspto-grants-2016_03 |