2-Benzothiazolinone, hydrazone → N'2-(1,3-benzothiazol-2yl)-5-nitro-2-furanecarbohydrazide

반응식

[N+:1]([C:4]1[O:8][C:7]([C:9](Cl)=[O:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].[NH:12]([C:14]1[S:15][C:16]2[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=2[N:18]=1)[NH2:13]>>[S:15]1[C:16]2[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=2[N:18]=[C:14]1[NH:12][NH:13][C:9]([C:7]1[O:8][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1)=[O:10]

참가 물질

반응물 2

HCID 119882-Benzothiazolinone, hydrazone

HCID 907115-Nitrofuroyl chloride

생성물 1

HCID 86664238N'2-(1,3-benzothiazol-2yl)-5-nitro-2-furanecarbohydrazide

반응 조건

온도: 0 °C

실험 절차

The compound 4a was prepared according to above described method by using 5-nitro-2-furancarboxylic acid chloride (300 mg, 1 mmol) and 2-hydrazino-benzothiazole (300 mg, 1.5 mmol) which stirred for 1 h at 0° C. and stirring continued at 25° C. for 11 h (yield 245 mg, 85%).

후처리

stirringstirring
waitcontinued at 25° C. for 11 h

출처 및 근거

ORD 기록: ord-18a36b4eaac74c44ab0531cb84dbbacf
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09273039B2

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