3-(Trifluoromethyl)phenylboronic acid → 2-(3-Fluoro-4-(3-(trifluoromethyl)phenoxy)phenyl)ethanol
반응식
[F:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][OH:10])[CH:5]=[CH:4][C:3]=1[OH:11].[F:12][C:13]([F:24])([F:23])[C:14]1[CH:15]=[C:16](B(O)O)[CH:17]=[CH:18][CH:19]=1>>[F:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][OH:10])[CH:5]=[CH:4][C:3]=1[O:11][C:18]1[CH:17]=[CH:16][CH:15]=[C:14]([C:13]([F:24])([F:23])[F:12])[CH:19]=1참가 물질
3
실험 절차
The title compound was prepared by a procedure similar to that described for D120 starting from 2-fluoro-4-(2-hydroxyethyl)phenol and (3-(trifluoromethyl)phenyl)boronic acid.
출처 및 근거
- ORD 기록
- ord-8b590d88d33943f3b43a20541d0ab770
- 출처 데이터셋
- uspto-grants-2016_03
- 특허 번호
- US09273054B2
반응 노트
불러오는 중…