HCID 67958464, 화합물 → HCID 71236583, 화합물

HRID 920390노트

반응식

HRID 920390 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[F:19])[O:5][C:6]1[CH:13]=[CH:12][C:11]([CH2:14][OH:15])=[CH:10][C:7]=1[C:8]#[N:9].Cl[C:21]1[CH:31]=[C:25]2[N:26]([CH3:30])[CH2:27][CH2:28][CH2:29][N:24]2[C:23](=[O:32])[N:22]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[F:19])[O:5][C:6]1[CH:13]=[CH:12][C:11]([CH2:14][O:15][C:21]2[CH:31]=[C:25]3[N:26]([CH3:30])[CH2:27][CH2:28][CH2:29][N:24]3[C:23](=[O:32])[N:22]=2)=[CH:10][C:7]=1[C:8]#[N:9]

참가 물질

3

반응물 2

HCID 67958464HCID 67958464, 화합물HCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

생성물 1

HCID 71236583HCID 71236583, 화합물

실험 절차

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 2-(3,4-difluorophenoxy)-5-(hydroxymethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

출처 및 근거

ORD 기록
ord-42848b27e9cb4677bd7054b7b5c6e507
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09273054B2

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