4-Chlorobenzyl alcohol → 8-((4-chlorobenzyl)oxy)-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][OH:9])=[CH:4][CH:3]=1.Cl[C:11]1[CH:23]=[C:15]2[N:16]([CH:20]([CH3:22])[CH3:21])[CH2:17][CH2:18][CH2:19][N:14]2[C:13](=[O:24])[N:12]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][O:9][C:11]2[CH:23]=[C:15]3[N:16]([CH:20]([CH3:21])[CH3:22])[CH2:17][CH2:18][CH2:19][N:14]3[C:13](=[O:24])[N:12]=2)=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 133974-Chlorobenzyl alcohol

HCID 717434708-Chloro-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

생성물 1

HCID 712367408-((4-chlorobenzyl)oxy)-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one

실험 절차

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (4-chlorophenyl)methanol and 8-chloro-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

출처 및 근거

ORD 기록: ord-c7f891bb17b546cda7754a17efa6962e
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09273054B2

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