참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | 4-Chloro-5-nitrophthalimide | HCID 2801129 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Amino-6-nitro-1H-isoindole-1,3(2H)-dione | HCID 15144568 | 92.5% |
반응 단계
A mixture of 5-chloro-6-nitroisoindoline-1,3-dione (28.0 g, 0.123 mol) and urea (73.8 g, 1.23 mol) was stirred and heated to 150° C. under argon for 6 h. After cooled to rt, the solid was suspended in hot water (100 mL, 80° C.), filtered, washed with hot water (3×50 mL) and dried under vacuum to give a yellow solid product, 23.56 g, 92.5% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09273055B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_03 |
|---|
| ORD ID | ord-ed47e73b7daf467f93712a427a8e6c1c |
|---|
| 출처 메모 | uspto-grants-2016_03 |
|---|
