Lactic Acid → HCID 86662333, 화합물

HRID 921990

반응식

HRID 921990 반응식
[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[OH:3].[OH-].[CH2:8]([P+:12]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:17][CH2:18][CH2:19][CH3:20])[CH2:13][CH2:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH3:11]>CC(C)=O>[C:1]([O-:6])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH2:21]([P+:12]([CH2:8][CH2:9][CH2:10][CH3:11])([CH2:13][CH2:14][CH2:15][CH3:16])[CH2:17][CH2:18][CH2:19][CH3:20])[CH2:22][CH2:23][CH3:24].[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[OH:3]

참가 물질

4

반응물 2

HCID 612Lactic AcidHCID 84487Phosphonium, tetrabutyl-, hydroxide (1:1)

생성물 1

HCID 86662333HCID 86662333, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Lactic acid (5-15 mmol) and tetrabutylphosphonium hydroxide (˜40% sol. in H2O) (3.414 g, 5 mmol) were dissolved in 20 ml of acetone and stirred for 15 min at room temperature. The solvent was evaporated and the remaining viscous liquid was dried at 0.1 mbar with stirring for 24 hrs. 1H-NMR (300 MHz, d6-DMSO) δ(ppm)=3.84 (br s, 1H), 3.44 (q, J=6.7 Hz, 1H), 2.18 (m, 8H), 1.41 (m, 16H), 1.05 (d, J=7.2 Hz, 3H), 0.91 (t, J=6.7 Hz, 12H). 31P-NMR (121.5 MHz, d6-DMSO) δ(ppm)=35.0. 13C-NMR (75 MHz, d6-DMSO) δ(ppm)=176.8, 67.3, 23.72 (d, J=15.5 Hz), 23.01 (d, J=4.7 Hz), 21.91, 17.70 (d, J=47.9 Hz), 13.62 (s).

후처리

  1. customThe solvent was evaporated
  2. customthe remaining viscous liquid was dried at 0.1 mbar
  3. stirringwith stirring for 24 hrs

출처 및 근거

ORD 기록
ord-e9c6d42dd0644bca9bd18c739c33c49e
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09278134B2

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