6-(1H-1,2,4-Triazol-1-yl)nicotinic acid → HCID 52946876, 화합물

HRID 922859노트

반응식

HRID 922859 반응식
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[N:15]1([C:20]2[N:25]=[CH:24][C:23]([C:26](O)=[O:27])=[CH:22][CH:21]=2)[CH:19]=[N:18][CH:17]=[N:16]1>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:26]([C:23]2[CH:24]=[N:25][C:20]([N:15]3[CH:19]=[N:18][CH:17]=[N:16]3)=[CH:21][CH:22]=2)=[O:27])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

참가 물질

3

반응물 2

HCID 42026406-(1H-1,2,4-Triazol-1-yl)nicotinic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

생성물 1

HCID 52946876HCID 52946876, 화합물

실험 절차

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline (40 mg) and 6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxylic acid to produce N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(1H-1,2,4-triazol-1-yl)pyridine-3-carboxamide. MS (Q1) 377.0 (M)+.

출처 및 근거

ORD 기록
ord-53a68be358524c8db52cee6071f98718
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09278961B2

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