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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 923111생성일: 2026년 10월 26일

1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/923111

반응식

참여 물질

역할이름HCID투입량
반응물1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acidHCID 4270263—
반응물4-Chloro-3-(pyridin-2-yl)anilineHCID 40151925—
생성물N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamideHCID 58614761—

반응 단계

50 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid via Procedure G. The product was purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide. MS (Q1) 407.0 (M)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09278961B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-e9842021494641f0aebfe1fca0259d30
출처 메모uspto-grants-2016_03