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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Tert-Butyl 4-(3-(Tert-Butyldisulfanyl)-2-(Isobutoxycarbonylamino)Propanamido)Piperidine-1-Carboxylate → Isobutyl 3-(Isopropyldisulfanyl)-1-Oxo-1-(Piperidin-4-ylamino)Propan-2-ylcarbamate

HRID 923721
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인쇄 미리보기

반응식

HRID 923721 반응식
[C:1]([S:5][S:6][CH2:7][CH:8]([NH:25][C:26]([O:28][CH2:29][CH:30]([CH3:32])[CH3:31])=[O:27])[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15](C(OC(C)(C)C)=O)[CH2:14][CH2:13]1)=[O:10])(C)([CH3:3])[CH3:2]>Cl.O1CCOCC1>[CH:1]([S:5][S:6][CH2:7][CH:8]([NH:25][C:26](=[O:27])[O:28][CH2:29][CH:30]([CH3:32])[CH3:31])[C:9](=[O:10])[NH:11][CH:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1)([CH3:3])[CH3:2]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

반응물 1

HCID 87107224Tert-Butyl 4-(3-(Tert-Butyldisulfanyl)-2-(Isobutoxycarbonylamino)Propanamido)Piperidine-1-Carboxylate

생성물 1

HCID 71572473Isobutyl 3-(Isopropyldisulfanyl)-1-Oxo-1-(Piperidin-4-ylamino)Propan-2-ylcarbamate

시약·촉매·용매 1

HCID 204431481,4-Dioxane hydrochloride용매

실험 절차

To the compound from Example 60 (7.085 g, 18.12 mmol) was added 30 ml of 4M HCl/Dioxane. The reaction was completed after 2 h at RT. The title compound was used for the next step without further purification.

후처리

  1. customThe title compound was used for the next step without further purification

출처 및 근거

ORD 기록
ord-e0ebc348c9da440287db5030fd9bbb32
출처 데이터셋
uspto-grants-2016_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US09278987B2

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