2-Bromoethanol → HCID 19622756, 화합물

반응식

[CH2:1]([O:3]C1C=C(C=O)C=C(O)C=1C(OC)=O)[CH3:2].[OH:17][C:18]1[CH:19]=[C:20]([CH:23]=[CH:24][C:25]=1[O:26][CH3:27])[CH:21]=[O:22].BrCCO>>[OH:3][CH2:1][CH2:2][O:17][C:18]1[CH:19]=[C:20]([CH:23]=[CH:24][C:25]=1[O:26][CH3:27])[CH:21]=[O:22]

참가 물질

반응물 3

HCID 108982-Bromoethanol

HCID 12127Isovanillin

HCID 86669344HCID 86669344, 화합물

생성물 1

HCID 19622756HCID 19622756, 화합물수율 62.5%

실험 절차

Followed procedure described in Intermediate 8, step 1 starting from 3-hydroxy-4-methoxybenzaldehyde and 2-bromoethanol with the reaction conditions of 90° C. overnight. Isolated 400 mg, yield 62.5%.

후처리

customIsolated 400 mg, yield 62.5%

출처 및 근거

ORD 기록: ord-da3bdb0875c343dfade086408b43bfaf
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09283213B2

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