Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → N-methacryloylglycylglycyl-thiazolidine-2-thione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| 반응물 | Methacryloylglycylglycine | HCID 10241886 | — |
| 반응물 | HCID 178527880 | HCID 178527880 | — |
| 촉매 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-methacryloylglycylglycyl-thiazolidine-2-thione | HCID 58455605 | — |
반응 단계
The synthesis of MA-GG-TT was similar to the synthesis of MA-GFLG-TT in Example 1. N-methacryloylglycylglycine (MA-GG-OH) was coupled with 2-mercaptothiazoline in DCM mediated by EDCI in presence of catalytic amount of DMAP. After reaction, the product was purified by recrystallization from MeOH solution.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09289510B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-7570d324d8d74bb897fc76c6c33cdc28 |
| 출처 메모 | uspto-grants-2016_03 |