3-(3-(2-(1-(3,4-dimethylphenyl)-1H-pyrazol-3-ylcarbamoyl)-4-(piperidin-1-yl)phenylcarbamoyl)-benzylthio)propanoic acid → 3-((3-((4-(Piperidin-1-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)benzyl)thio)propanoic acid

반응식

Cl[C:2]1[CH:3]=[CH:4][C:5]([N+:26]([O-])=O)=[C:6]([CH:25]=1)[C:7]([NH:9][C:10]1[CH:14]=[CH:13][N:12]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=2)[N:11]=1)=[O:8].CC1C=C(N2C=CC(NC(C3C=C(N4CCCCC4)C=CC=3N[C:58]([C:60]3[CH:61]=[C:62]([CH:70]=[CH:71][CH:72]=3)[CH2:63][S:64][CH2:65][CH2:66][C:67]([OH:69])=[O:68])=[O:59])=O)=N2)C=CC=1C.ClC1C=CC([N+]([O-])=O)=C(C=1)C(NC1C=C[N:84]([C:87]2[CH:92]=[CH:91][C:90]([CH3:93])=C(C)C=2)N=1)=O>>[N:84]1([C:2]2[CH:3]=[CH:4][C:5]([NH:26][C:58]([C:60]3[CH:61]=[C:62]([CH:70]=[CH:71][CH:72]=3)[CH2:63][S:64][CH2:65][CH2:66][C:67]([OH:69])=[O:68])=[O:59])=[C:6]([C:7](=[O:8])[NH:9][C:10]3[CH:14]=[CH:13][N:12]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=4)[N:11]=3)[CH:25]=2)[CH2:87][CH2:92][CH2:91][CH2:90][CH2:93]1