Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium sulfate decahydrate → (4-Phenylsulfanylmethyl-phenyl)-methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium sulfate decahydrate | HCID 62649 | — |
| 반응물 | Methyl 4-(phenylsulfanylmethyl)benzoate | HCID 366566 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | (4-Phenylsulfanylmethyl-phenyl)-methanol | HCID 59255239 | 95.4% |
반응 단계
Methyl 4-(phenylsulfanylmethyl)benzoate (1.07 g) was dissolved in THF (14 mL), added with lithium aluminum hydride (200 mg) in small portions under ice cooling, and stirred for 40 minutes at the same temperature. Under ice cooling, sodium sulfate decahydrate was added in small portions and filtered through Celite. The solvent was evaporated under reduced pressure. The residues were suspended in hexane and collected by filtration to obtain the title compound (910 mg) as a white powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09290440B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-515455be59cd4491a9782fc76afb926c |
| 출처 메모 | uspto-grants-2016_03 |