Methyl 2-amino-2-methylpropanoate → Methyl 2-(5-cyclopropyl-6-(2,4-dichlorophenylamino)picolinamido)-2-methylpropanoate

HRID 927339

반응식

HRID 927339 반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:19](O)=[O:20])=[N:8][C:9]=2[NH:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])[CH2:3][CH2:2]1.[CH3:22][O:23][C:24](=[O:29])[C:25]([CH3:28])([CH3:27])[NH2:26]>>[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:19]([NH:26][C:25]([CH3:28])([CH3:27])[C:24]([O:23][CH3:22])=[O:29])=[O:20])=[N:8][C:9]=2[NH:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 4186341Methyl 2-amino-2-methylpropanoateHCID 710872815-Cyclopropyl-6-(2,4-dichloro-phenylamino)-pyridine-2-carboxylic acid

생성물 1

HCID 71087541Methyl 2-(5-cyclopropyl-6-(2,4-dichlorophenylamino)picolinamido)-2-methylpropanoate

실험 절차

The title compound was synthesized in analogy to Example 4 b, using 5-cyclopropyl-6-(2,4-dichloro-phenylamino)-pyridine-2-carboxylic acid and 2-methyl-alanine methyl ester as starting materials, MS (EI): m/e 422.1 [M+H]+.

출처 및 근거

ORD 기록
ord-f244c926d23d48a4bcf1d5cb45d3da7b
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290451B2

연결된 노트

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