Methyl 2-amino-2-methylpropanoate → HCID 178500511, 화합물

반응식

[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)[CH2:3][CH2:2]1.[CH3:20][O:21][C:22](=[O:27])[C:23]([CH3:26])([CH3:25])[NH2:24]>>[CH3:20][O:21][C:22](=[O:27])[C:23]([NH:24][C:12]([C:10]1[CH:9]=[CH:8][C:7]([C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])([CH3:26])[CH3:25]

참가 물질

반응물 2

HCID 4186341Methyl 2-amino-2-methylpropanoate

HCID 178524221HCID 178524221, 화합물

생성물 1

HCID 178500511HCID 178500511, 화합물

실험 절차

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(1H-pyrazol-3-yl)-pyridine-2-carboxylic acid and 2-methyl-alanine methyl ester as starting materials, MS (LC/MS): 359.1 [M+H]+.

출처 및 근거

ORD 기록: ord-f762fc3b9ed14b4ea691d9d33d39d78b
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09290451B2

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