5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid → HCID 71087666, 화합물

HRID 927674

반응식

HRID 927674 반응식
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:17]([OH:19])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[CH2:3][CH2:2]1.Cl.[NH2:21][C:22]([CH2:29][CH3:30])([CH2:27][CH3:28])[C:23]([O:25][CH3:26])=[O:24]>>[CH3:26][O:25][C:23](=[O:24])[C:22]([NH:21][C:17]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[N:8]=1)=[O:19])([CH2:29][CH3:30])[CH2:27][CH3:28]

참가 물질

3

반응물 2

HCID 710872545-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acidHCID 75488114Methyl 2-amino-2-ethylbutanoate hydrochloride

생성물 1

HCID 71087666HCID 71087666, 화합물

실험 절차

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 166 b) and methyl 2-amino-2-ethylbutanoate hydrochloride (CAN 92398-54-4) as starting materials, MS (EI): m/e=391.3 [M+H]+.

출처 및 근거

ORD 기록
ord-bcca540f443045bc8275dd525c88daa7
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290451B2

연결된 노트

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